PROCESS FOR PREPARING MACROCYCLIC CHELATING AGENTS AND FORMATION OF CHELATES AND CONJUGATES THEREOF - Patent 0662842

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EP 0 662 842 A1

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(43)	Date of publication:
	19.07.1995 Bulletin 1995/29

(21)	Application number: 93912231.0

(22)	Date of filing: 13.04.1993

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International Patent Classification (IPC):

C12P 21/ 08^{( . )}
A61K 51/ 00^{( . )}
A61K 51/ 10^{( . )}
C07F 9/ 6515^{( . )}
C07K 14/ 00^{( . )}

A61K 39/ 44^{( . )}
A61K 51/ 04^{( . )}
C07D 257/ 02^{( . )}
C07F 9/ 6524^{( . )}
C07K 16/ 00^{( . )}

(86)	International application number:
	PCT/US1993/003483

(87)	International publication number:
	WO 1993/020852 (28.10.1993 Gazette 1993/26)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE

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Priority:

13.04.1992 US 19920868078

(71)	Applicant: THE DOW CHEMICAL COMPANY
	Midland, Michigan 48640 (US)

(72)	Inventors:
	CHENG, Roberta C. Midland, MI 48642 (US) FORDYCE, William A. Midland, MI 48642 (US) KRUPER, William J., Jr. Sanford, MI 48657 (US) LITWINSKI, George R. Midland, MI 48642 (US)

(74)	Representative: Burford, Anthony Frederick
	W.H. Beck, Greener & Co. 7 Stone Buildings Lincoln's Inn London WC2A 3SZ London WC2A 3SZ (GB)

(54)	PROCESS FOR PREPARING MACROCYCLIC CHELATING AGENTS AND FORMATION OF CHELATES AND CONJUGATES THEREOF