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EP 0 664 000 A1

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(43) Date of publication: 26.07.1995 Bulletin 1995/30 (21) Application number: 93921623.0 (22) Date of filing: 16.09.1993

(51) International Patent Classification (IPC):  G01N 33/ 48( . ) G01N 33/ 53( . ) B01L 3/ 00( . ) G01N 33/ 543( . ) (86) International application number: PCT/US1993/008751 (87) International publication number: WO 1994/009366 (28.04.1994 Gazette 1994/10)

(84) Designated Contracting States: BE CH DE ES FR GB IT LI (30) Priority: 08.10.1992 US 19920958068 (71) Applicant: ABBOTT LABORATORIES Abbott Park, Illinois 60064-3500 (US)

(72) Inventors: FORNEY, Kevin, J. Kenosha, WI 53143 (US) GEIST, Jill, M. Ingleside, IL 60041 (US) LOOMIS, Neil, W. Racine, WI 53403 (US) MORICI, Laura, S. Cary, IL 60013 (US) MUETTERTIES, Andrew, J. Mundelein, IL 60060 (US) PARSONS, Robert, G. Green Oaks, IL 60048 (US) PUTMAN, Jill, M. Round Lake Beach, IL 60073 (US) ROPELLA, Paul, J. Racine, WI 53405 (US) SCHAPIRA, Thomas, G. Bristol, WI 53104 (US) SIEGEL, Neal, A. Deerfield, IL 60015 (US) WAGNER, Brian, K. Milwaukee, WI 53233 (US) BASORE, Bob, O. Toledo, OH 43617 (US) (74) Representative: Modiano, Guido, Dr.-Ing., et al  Modiano, Josif, Pisanty & Staub, Baaderstrasse 3 D-80469 München D-80469 München (DE)