(19)
(11) EP 0 664 810 A1

(12)

(43) Date of publication:
02.08.1995 Bulletin 1995/31

(21) Application number: 93923238.0

(22) Date of filing: 12.10.1993
(51) International Patent Classification (IPC): 
A61K 31/ 41( . )
A61K 31/ 535( . )
A61K 31/ 55( . )
A61P 25/ 28( . )
C07D 487/ 06( . )
C07D 513/ 06( . )
A61K 31/ 495( . )
A61K 31/ 54( . )
A61P 25/ 00( . )
C07D 471/ 06( . )
C07D 498/ 06( . )
(86) International application number:
PCT/US1993/009476
(87) International publication number:
WO 1994/009009 (28.04.1994 Gazette 1994/10)
(84) Designated Contracting States:
DE ES FR GB IT

(30) Priority: 13.10.1992 US 19920960522

(71) Applicant: THE DU PONT MERCK PHARMACEUTICAL COMPANY
Wilmington, Delaware 19898 (US)

(72) Inventors:
  • EARL, Richard, Alan
    Wilmington, DE 19810 (US)
  • MYERS, Melvyn, John
    Middletown, CT 06457 (US)

(74) Representative: von Kreisler, Alek, Dipl.-Chem., et al 
Patentanwälte, von Kreisler-Selting-Werner, Bahnhofsvorplatz 1 (Deichmannhaus)
D-50667 Köln
D-50667 Köln (DE)

   


(54) 3,3-DISUBSTITUTED TRI- AND TETRACYCLIC INDOLIN-2-ONES USEFUL FOR THE TREATMENT OF COGNITIVE DISORDERS