(19)

(11)

EP 0 665 855 A1

(12)

(43) Date of publication: 09.08.1995 Bulletin 1995/32 (21) Application number: 93924216.0 (22) Date of filing: 13.10.1993

(51) International Patent Classification (IPC):  A61L 27/ 18( . ) C08G 18/ 32( . ) C09J 175/ 12( . ) A61L 31/ 06( . ) C09J 175/ 04( . ) G02B 1/ 04( . ) (86) International application number: PCT/NL1993/000203 (87) International publication number: WO 1994/009048 (28.04.1994 Gazette 1994/10)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB IT LI LU NL SE (30) Priority: 13.10.1992 NL 19920001773 (71) Applicant: Rijksuniversiteit te Groningen NL-9712 CP Groningen (NL)	(72) Inventors: PENNINGS, Albert Johannes NL-9712 CP Groningen (NL) BRUIN, Peter NL-9712 CP Groningen (NL) BOS, Machiel NL-9712 CP Groningen (NL) (74) Representative: Smulders, Theodorus A.H.J., Ir., et al  Vereenigde Octrooibureaux Nieuwe Parklaan 97 NL-2587 BN 's-Gravenhage NL-2587 BN 's-Gravenhage (NL)