(19)
(11) EP 0 666 867 A1

(12)

(43) Date of publication:
16.08.1995 Bulletin 1995/33

(21) Application number: 93921548.0

(22) Date of filing: 14.09.1993
(51) International Patent Classification (IPC): 
A61K 38/ 00( . )
A61P 29/ 00( . )
C07K 14/ 74( . )
A61K 39/ 395( . )
C07K 7/ 08( . )
C07K 16/ 28( . )
(86) International application number:
PCT/US1993/008644
(87) International publication number:
WO 1994/006823 (31.03.1994 Gazette 1994/08)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 14.09.1992 US 19920943418

(71) Applicant: BRIGHAM AND WOMEN'S HOSPITAL
Boston, Massachusetts 02115 (US)

(72) Inventors:
  • BRENNER, Michael, B.
    Sherborn, MA 01770 (US)
  • DERSIMONIAN, Harout
    Watertown, MA 02172 (US)

(74) Representative: Sheard, Andrew Gregory, et al 
Kilburn & Strode 30, John Street
London WC1N 2DD
London WC1N 2DD (GB)

   


(54) REAGENTS AND METHODS FOR TREATING RHEUMATOID ARTHRITIS