(19)
(11) EP 0 667 789 A1

(12)

(43) Date of publication:
23.08.1995 Bulletin 1995/34

(21) Application number: 93921492.0

(22) Date of filing: 16.09.1993
(51) International Patent Classification (IPC): 
A61K 38/ 20( . )
A61P 31/ 12( . )
C07K 14/ 54( . )
A61K 38/ 00( . )
A61K 39/ 395( . )
A61P 37/ 04( . )
C07K 16/ 24( . )
(86) International application number:
PCT/US1993/008562
(87) International publication number:
WO 1994/006473 (31.03.1994 Gazette 1994/08)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 18.09.1992 US 19920947316

(71) Applicants:
  • SCHERING CORPORATION
    Kenilworth, NJ 07030 (US)
  • THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the Secretary of the Department of Health and Human Services
    Bethesda, Maryland 20892 (US)

(72) Inventors:
  • CLERICI, Mario
    Rockville, MD 20852 (US)
  • COFFMAN, Robert L.
    Portola Valley, CA 94028 (US)
  • SHEARER, Gene M.
    Bethesda, MD 20817 (US)

(74) Representative: Thomson, Paul Anthony 
Potts, Kerr & Co. 15, Hamilton Square
Birkenhead Merseyside L41 6BR
Birkenhead Merseyside L41 6BR (GB)

   


(54) RESTORATION OF IMMUNOCOMPETENCY TO T HELPER CELLS IN HIV INFECTED PATIENTS