$g(a)-SUBSTITUTED POLYPEPTIDES HAVING THERAPEUTIC ACTIVITY

(19)

(11)

EP 0 668 770 A1

(12)

(43)	Date of publication:
	30.08.1995 Bulletin 1995/35

(21)	Application number: 92911434.0

(22)	Date of filing: 15.04.1992

(51)

International Patent Classification (IPC):

A61K 38/ 00^{( . )}
A61P 1/ 04^{( . )}
A61P 9/ 00^{( . )}
A61P 11/ 00^{( . )}
A61P 15/ 00^{( . )}
A61P 25/ 04^{( . )}
A61P 25/ 24^{( . )}
A61P 25/ 28^{( . )}
A61P 35/ 00^{( . )}
C07K 5/ 06^{( . )}
C07K 5/ 078^{( . )}
C07K 5/ 09^{( . )}
C07K 5/ 10^{( . )}
C07K 5/ 113^{( . )}
C07K 14/ 66^{( . )}

A61K 38/ 22^{( . )}
A61P 3/ 04^{( . )}
A61P 9/ 12^{( . )}
A61P 13/ 02^{( . )}
A61P 25/ 00^{( . )}
A61P 25/ 20^{( . )}
A61P 25/ 26^{( . )}
A61P 29/ 00^{( . )}
A61P 43/ 00^{( . )}
C07K 5/ 065^{( . )}
C07K 5/ 08^{( . )}
C07K 5/ 097^{( . )}
C07K 5/ 107^{( . )}
C07K 7/ 06^{( . )}
C07K 14/ 70^{( . )}

(86)	International application number:
	PCT/US1992/003119

(87)	International publication number:
	WO 1992/019254 (12.11.1992 Gazette 1992/28)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IT LI LU MC NL SE

(30)

Priority:

24.04.1991 US 19910690755
20.03.1992 US 19920852086

(71)	Applicant: WARNER-LAMBERT COMPANY
	Ann Arbor, Michigan 48105 (US)

(72)	Inventors:
	HORWELL, David, Christopher Cambridge CBS 0HT (GB) HUGUES, John Cambridge CB5 OHT (GB) RICHARDSON, Reginald, Stewart Suffolk CB9 OLV (GB) HOWSON, William Weston Colville Cambridge Shire (GB)

(74)	Representative: Mansmann, Ivo, et al
	Gödecke AG Mooswaldallee 1-9 D-79090 Freiburg D-79090 Freiburg (DE)

(54)	$g(a)-SUBSTITUTED POLYPEPTIDES HAVING THERAPEUTIC ACTIVITY