SYNTHESIS AND PURIFICATION OF TRUNCATED AND MUTEIN FORMS OF HUMAN CILIARY NEURONOTROPHIC FACTOR - Patent 0668911

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EP 0 668 911 A1

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(43)	Date of publication:
	30.08.1995 Bulletin 1995/35

(21)	Application number: 92923337.0

(22)	Date of filing: 11.11.1992

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International Patent Classification (IPC):

C12N 15/ 09^{( . )}
A61P 25/ 00^{( . )}
C07K 14/ 475^{( . )}
C12N 1/ 21^{( . )}
C12P 21/ 02^{( . )}

A61K 38/ 00^{( . )}
C07K 1/ 22^{( . )}
C07K 14/ 52^{( . )}
C12N 15/ 12^{( . )}
C12R 1/ 19^{( . )}

(86)	International application number:
	PCT/EP1992/002586

(87)	International publication number:
	WO 1993/010233 (27.05.1993 Gazette 1993/13)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL SE

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Priority:

11.11.1991 IT 1991PD00207
20.05.1992 IT 1992PD00087

(71)	Applicant: FIDIA S.p.A.
	I-35031 Abano Terme (Padova) (IT)

(72)	Inventors:
	CALLEGARO, Lanfranco I-35020 Ponte di Brenta (IT) NEGRO, Alessandro I-35100 Padova (IT)

(74)	Representative: Huber, Bernhard, Dipl.-Chem., et al
	Patentanwälte H. Weickmann, Dr. K. Fincke F.A. Weickmann, B. Huber Dr. H. Liska, Dr. J. Prechtel, Dr. B. Böhm, Kopernikusstrasse 9 D-81679 München D-81679 München (DE)

(54)	SYNTHESIS AND PURIFICATION OF TRUNCATED AND MUTEIN FORMS OF HUMAN CILIARY NEURONOTROPHIC FACTOR