(19)
(11) EP 0 669 985 A1

(12)

(43) Date of publication:
06.09.1995 Bulletin 1995/36

(21) Application number: 94902202.0

(22) Date of filing: 02.11.1993
(51) International Patent Classification (IPC): 
C12N 15/ 09( . )
A61K 47/ 48( . )
C07K 14/ 315( . )
C12N 1/ 21( . )
C12N 15/ 63( . )
C12P 21/ 02( . )
C12R 1/ 865( . )
A61K 39/ 09( . )
A61P 31/ 04( . )
C12N 1/ 19( . )
C12N 15/ 31( . )
C12N 15/ 70( . )
C12R 1/ 19( . )
(86) International application number:
PCT/US1993/010506
(87) International publication number:
WO 1994/010317 (11.05.1994 Gazette 1994/11)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 02.11.1992 US 19920968866

(71) Applicants:
  • THE GENERAL HOSPITAL CORPORATION
    Boston, MA 02114 (US)
  • BRIGHAM AND WOMEN'S HOSPITAL
    Boston, Massachusetts 02115 (US)

(72) Inventors:
  • MICHEL, James L.
    Waban, MA 02168 (US)
  • KASPER, Dennis L.
    Newton Centre, MA 02159 (US)
  • AUSUBEL, Frederick M.
    Newton, MA 02161 (US)
  • MADOFF, Lawrence C.
    Boston, MA 02116 (US)

(74) Representative: Fischer, Hans-Jürgen, Dr. 
Hoechst AG Patent- und Lizenzabteilung Gebäude K 801
D-65926 Frankfurt am Main
D-65926 Frankfurt am Main (DE)

   


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