(19)
(11) EP 0 670 734 A1

(12)

(43) Date of publication:
13.09.1995 Bulletin 1995/37

(21) Application number: 93924919.0

(22) Date of filing: 12.10.1993
(51) International Patent Classification (IPC): 
A61K 39/ 395( . )
C07K 14/ 705( . )
A61K 38/ 00( . )
A61P 29/ 00( . )
C07K 16/ 28( . )
(86) International application number:
PCT/US1993/009777
(87) International publication number:
WO 1994/008620 (28.04.1994 Gazette 1994/10)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 09.10.1992 US 19920958904
22.10.1992 US 19920964156

(71) Applicant: CENTER FOR BLOOD RESEARCH, INC.
Boston, MA 02115 (US)

(72) Inventors:
  • DIAMOND, Michael
    Cambridge, MA 02138 (US)
  • SPRINGER, Timothy A.
    Chestnut Hill, MA 02167 (US)

(74) Representative: Laudien, Dieter, Dr. 
Boehringer Ingelheim International GmbH ZA Patente Postfach 200
55216 Ingelheim am Rhein
55216 Ingelheim am Rhein (DE)

   


(54) A SUBPOPULATION OF MAC-1 (CD11B/CD18) MOLECULES WHICH MEDIATE NEUTROPHIL ADHESION TO ICAM-1 AND FIBRINOGEN