IMMUNOLOGICAL PURGING OF TUMOR CELLS FROM BONE MARROW USING MICROSPHERES AND MONOCLONAL ANTIBODIES - Patent 0671950

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EP 0 671 950 A1

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(43)	Date of publication:
	20.09.1995 Bulletin 1995/38

(21)	Application number: 93923903.0

(22)	Date of filing: 18.10.1993

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International Patent Classification (IPC):

G01N 33/ 577^{( . )}
A61K 39/ 395^{( . )}
A61P 35/ 00^{( . )}
C07K 16/ 18^{( . )}
C07K 16/ 30^{( . )}
A61K 38/ 00^{( . )}

A61K 9/ 50^{( . )}
A61K 39/ 44^{( . )}
A61P 35/ 02^{( . )}
C07K 16/ 28^{( . )}
C12P 21/ 08^{( . )}

(86)	International application number:
	PCT/US1993/009891

(87)	International publication number:
	WO 1994/008621 (28.04.1994 Gazette 1994/10)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

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Priority:

19.10.1992 US 19920963104

(71)	Applicant: DANA FARBER CANCER INSTITUTE
	Boston Massachusetts 02115 (US)

(72)	Inventors:
	SCHLOSSMAN, Stuart, F. Newton Center, MA 02130 (US) NADLER, Lee, M. Newton, MA 02159 (US) FREEDMAN, Arnold, S. Boston, MA 02115 (US)

(74)	Representative: Robert, Jean S.
	Case postale 152 CH-1257 Landecy (Genève) CH-1257 Landecy (Genève) (CH)

(54)	IMMUNOLOGICAL PURGING OF TUMOR CELLS FROM BONE MARROW USING MICROSPHERES AND MONOCLONAL ANTIBODIES