(19)
(11) EP 0 672 171 A1

(12)

(43) Date of publication:
20.09.1995 Bulletin 1995/38

(21) Application number: 92919326.0

(22) Date of filing: 27.08.1992
(51) International Patent Classification (IPC): 
C07H 21/ 04( . )
C12N 15/ 00( . )
C12Q 1/ 68( . )
C07H 21/ 00( . )
C12N 15/ 113( . )
(86) International application number:
PCT/US1992/007246
(87) International publication number:
WO 1993/005180 (18.03.1993 Gazette 1993/08)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL SE

(30) Priority: 30.08.1991 US 19910751813

(71) Applicant: THE JOHNS HOPKINS UNIVERSITY
Baltimore, MD 21218-2692 (US)

(72) Inventors:
  • MILLER, Paul, S.
    Baltimore, MD 21212 (US)
  • BHAN, Purshotam
    Ellicott City, MD 21042-5002 (US)

(74) Representative: Goldin, Douglas Michael, et al 
J.A. KEMP & CO. 14, South Square Gray's Inn
London WC1R 5LX
London WC1R 5LX (GB)

   


(54) FORMATION OF TRIPLE HELIX COMPLEXES OF DOUBLE STRANDED DNA USING NUCLEOSIDE OLIGOMERS WHICH COMPRISE PURINE BASE ANALOGS