(19)
(11) EP 0 673 385 A1

(12)

(43) Date of publication:
27.09.1995 Bulletin 1995/39

(21) Application number: 93920048.0

(22) Date of filing: 13.08.1993
(51) International Patent Classification (IPC): 
C07K 5/ 103( . )
C12N 15/ 85( . )
 C07K 14/ 47( . )
A61K 38/ 00( . )
(86) International application number:
PCT/US1993/007643
(87) International publication number:
WO 1994/004562 (03.03.1994 Gazette 1994/06)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 13.08.1992 US 19920928920

(71) Applicant: THE GENERAL HOSPITAL CORPORATION
Boston, MA 02114 (US)

(72) Inventors:
  • FISHMAN, Mark, C.
    Newton Centre, MA 02159 (US)
  • FEDEROFF, Howard
    Mamaronneck, NY 10543 (US)
  • ZUBER, Mauricio
    Fort Collins, CO 80526 (US)
  • STRITTMATTER, Stephen
    Charlestown, MA 02129 (US)
  • VALENZUELA, Dario
    Somerville, MA 02134 (US)
  • NG, Shi-Chung
    Lawrenceville, NJ 08648 (US)
  • GRABCZYK, Edward
    Cambridge, MA 02139 (US)

(74) Representative: Chapman, Paul William, et al 
Kilburn & Strode, 30 John Street
London WC1N 2DD
London WC1N 2DD (GB)

   


(54) MAMMALIAN GAP-43 COMPOSITIONS AND METHODS OF USE