ANTISENSE OLIGONUCLEOTIDES TO INHIBIT EXPRESSION OF MUTATED AND WILD TYPE GENES FOR COLLAGEN - Patent 0674705

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EP 0 674 705 A1

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(43)	Date of publication:
	04.10.1995 Bulletin 1995/40

(21)	Application number: 94901327.0

(22)	Date of filing: 09.11.1993

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International Patent Classification (IPC):

C12N 15/ 09^{( . )}
A61K 31/ 7088^{( . )}
A61P 1/ 16^{( . )}
A61P 17/ 00^{( . )}
C12N 15/ 113^{( . )}

A61K 31/ 70^{( . )}
A61K 48/ 00^{( . )}
A61P 11/ 00^{( . )}
C07H 21/ 04^{( . )}

(86)	International application number:
	PCT/US1993/010756

(87)	International publication number:
	WO 1994/011494 (26.05.1994 Gazette 1994/12)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

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Priority:

09.11.1992 US 19920973332

(71)	Applicant: THOMAS JEFFERSON UNIVERSITY
	Philadelphia Pennsylvania 19107 (US)

(72)	Inventors:
	PROCKOP, Darwin Philadelphia, PA 19106 (US) COLIGE, Alain SarttTilman 13-4000, B-Par Liege 1 (BE) BASERGA, Renato Ardmore, PA 19003 (US) NUGENT, Paul Chestnut Hill, PA 19118 (US)

(74)	Representative: Hallybone, Huw George, et al
	CARPMAELS AND RANSFORD 43 Bloomsbury Square London WC1A 2RA London WC1A 2RA (GB)

(54)	ANTISENSE OLIGONUCLEOTIDES TO INHIBIT EXPRESSION OF MUTATED AND WILD TYPE GENES FOR COLLAGEN