(19)
(11) EP 0 675 723 A1

(12)

(43) Date of publication:
11.10.1995 Bulletin 1995/41

(21) Application number: 94905419.0

(22) Date of filing: 17.12.1993
(51) International Patent Classification (IPC): 
A61K 31/ 565( . )
A61P 43/ 00( . )
A61K 31/ 66( . )
(86) International application number:
PCT/US1993/012302
(87) International publication number:
WO 1994/014455 (07.07.1994 Gazette 1994/15)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE

(30) Priority: 23.12.1992 US 19920996418

(71) Applicant: MERCK & CO. INC.
Rahway New Jersey 07065-0900 (US)

(72) Inventor:
  • WHITEFORD, Donna, T.
    Brooklyn, NY 11201 (US)

(74) Representative: Cole, William Gwyn 
European Patent Department Merck & Co., Inc. Terlings Park Eastwick Road
Harlow Essex CM20 2QR
Harlow Essex CM20 2QR (GB)

   


(54) BISPHOSPHONATE/ESTROGEN THERAPY FOR TREATING AND PREVENTING BONE LOSS