(19)

(11)

EP 0 675 731 A1

(12)

(43) Date of publication: 11.10.1995 Bulletin 1995/41 (21) Application number: 94930888.0 (22) Date of filing: 21.10.1994

(51) International Patent Classification (IPC):  A61K 38/ 08( . ) C07K 7/ 08( . ) C07K 7/ 06( . ) A61K 38/ 00( . ) (86) International application number: PCT/CA1994/000590 (87) International publication number: WO 1995/011038 (27.04.1995 Gazette 1995/18)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 22.10.1993 US 19930139757 (71) Applicant: Allelix Biopharmaceuticals Inc. Mississauga, Ontario, L4V 1V7 (CA)	(72) Inventors: TWIST, Michael deceased (CA) SUMNER-SMITH, Martin Bolton, Ontario L7E 3V4 (CA) (74) Representative: Browne, Robin Forsythe, Dr., et al  Urquhart-Dykes & Lord Tower House Merrion Way Leeds LS2 8PA West Yorkshire Leeds LS2 8PA West Yorkshire (GB)