(19)
(11) EP 0 675 737 A1

(12)

(43) Date of publication:
11.10.1995 Bulletin 1995/41

(21) Application number: 94905922.0

(22) Date of filing: 06.12.1993
(51) International Patent Classification (IPC): 
G01N 33/ 53( . )
A61K 49/ 00( . )
A61K 51/ 10( . )
C12N 9/ 06( . )
G01N 33/ 535( . )
G01N 33/ 574( . )
A61K 47/ 48( . )
A61K 51/ 00( . )
C12N 1/ 21( . )
G01N 33/ 532( . )
G01N 33/ 573( . )
C12R 1/ 19( . )
(86) International application number:
PCT/US1993/011842
(87) International publication number:
WO 1994/013327 (23.06.1994 Gazette 1994/14)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 15.12.1992 US 19920990423

(71) Applicant: THE WELLCOME FOUNDATION LIMITED
London NW1 2BP (GB)

(72) Inventors:
  • SNOW, Robert A.
    West Chester, PA 19380 (US)
  • KRUSE, Lawrence I.
    Haddonfield, NJ 08033 (US)
  • BLACK, Christopher D.V.
    Silver Spring, MD 20906 (US)
  • SHEARMAN, Clyde W.
    West Chester, PA 19382 (US)

(74) Representative: Baker-Munton, Nicola Jane, et al 
The Wellcome Foundation Limited Langley Court
Beckenham Kent BR3 3BS
Beckenham Kent BR3 3BS (GB)

   


(54) IMMUNOREACTIVE REAGENTS EMPLOYING DIHYDROFOLATE REDUCTASE