(19)

(11)

EP 0 676 934 A1

(12)

(43) Date of publication: 18.10.1995 Bulletin 1995/42 (21) Application number: 93914874.0 (22) Date of filing: 05.07.1993

(51) International Patent Classification (IPC):  A61B 19/ 04( . ) A61F 6/ 04( . ) (86) International application number: PCT/GB1993/001397 (87) International publication number: WO 1994/002080 (03.02.1994 Gazette 1994/04)

(84) Designated Contracting States: DE ES FR GB IT (30) Priority: 16.07.1992 GB 19920015117 (71) Applicant: ISIS INNOVATION LIMITED Oxford OX1 3UB (GB)	(72) Inventor: BULSTRODE, Christopher John Kent Wheatley, Oxfordshire OX3 31NX (GB) (74) Representative: Pennant, Pyers, et al  Stevens, Hewlett & Perkins 1 Serjeants' Inn Fleet Street London EC4Y 1LL London EC4Y 1LL (GB)