HYDANTOIN AND SUCCINIMIDE-SUBSTITUTED DERIVATIVES OF SPIROINDANYLCAMPHORSULFONYL OXYTOCIN ANTAGONISTS - Patent 0679084

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EP 0 679 084 A1

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(43)	Date of publication:
	02.11.1995 Bulletin 1995/44

(21)	Application number: 94905516.0

(22)	Date of filing: 23.12.1993

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International Patent Classification (IPC):

C07D 295/ 22^{( . )}
A61K 31/ 443^{( . )}
A61K 31/ 495^{( . )}
A61P 15/ 00^{( . )}
C07D 207/ 273^{( . )}
C07D 207/ 416^{( . )}
C07D 295/ 26^{( . )}
C07D 401/ 14^{( . )}
C07D 405/ 06^{( . )}
C07D 471/ 10^{( . )}
C07D 498/ 04^{( . )}

A61K 31/ 4427^{( . )}
A61K 31/ 445^{( . )}
A61P 13/ 02^{( . )}
C07D 207/ 27^{( . )}
C07D 207/ 40^{( . )}
C07D 221/ 20^{( . )}
C07D 401/ 12^{( . )}
C07D 403/ 14^{( . )}
C07D 405/ 14^{( . )}
C07D 487/ 04^{( . )}
C07F 9/ 6558^{( . )}

(86)	International application number:
	PCT/US1993/012565

(87)	International publication number:
	WO 1994/014438 (07.07.1994 Gazette 1994/15)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE

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Priority:

23.12.1992 US 19920993861

(71)	Applicant: MERCK & CO. INC.
	Rahway New Jersey 07065-0900 (US)

(72)	Inventors:
	GILBERT, Kevin Bechtelsville, PA 19505 (US) HOBBS, Doug, W. Lansdale, PA 19446 (US) VEBER, Daniel, F. Ambler, PA 19002 (US) WILLIAMS, Peter, D. Harleysville, PA 19438 (US) EVANS, Ben, E. Lansdale, PA 19446 (US)

(74)	Representative: Cole, William Gwyn, et al
	European Patent Department Merck & Co., Inc. Terlings Park Eastwick Road Harlow Essex CM20 2QR Harlow Essex CM20 2QR (GB)

(54)	HYDANTOIN AND SUCCINIMIDE-SUBSTITUTED DERIVATIVES OF SPIROINDANYLCAMPHORSULFONYL OXYTOCIN ANTAGONISTS