(19)
(11) EP 0 682 656 A1

(12)

(43) Date of publication:
22.11.1995 Bulletin 1995/47

(21) Application number: 94905697.0

(22) Date of filing: 25.01.1994
(51) International Patent Classification (IPC): 
A61K 31/ 44( . )
A61K 31/ 4409( . )
A61P 25/ 00( . )
C07D 213/ 40( . )
C07D 215/ 38( . )
C07D 215/ 46( . )
A61K 31/ 4406( . )
A61K 31/ 47( . )
A61P 43/ 00( . )
C07D 213/ 75( . )
C07D 215/ 42( . )
(86) International application number:
PCT/EP1994/000189
(87) International publication number:
WO 1994/018170 (18.08.1994 Gazette 1994/19)
(84) Designated Contracting States:
BE CH DE FR GB IT LI NL

(30) Priority: 05.02.1993 GB 19930002275

(71) Applicant: SMITHKLINE BEECHAM PLC
Brentford, Middlesex TW8 9EP (GB)

(72) Inventors:
  • FORBES, Ian Thomson, SmithKline Beecham Pharma.
    Harlow, Essex CM19 5AD (GB)
  • HAM, Peter, SmithKline Beecham Pharma.
    Harlow, Essex CM19 5AD (GB)
  • MARTIN, Roger Thomas, SmithKline Beecham Pharma.
    Harlow, EssexCM19 x5AD (GB)
  • THOMPSON, Mervyn, SmithKline Beecham Pharma.
    Harlow, Essex CM195AD 9 (GB)

(74) Representative: Summersell, Richard John, et al 
SmithKline Beecham Corporate Intellectual Property SB House Great West Road
Brentford, Middlesex TW8 9BD
Brentford, Middlesex TW8 9BD (GB)

   


(54) USE OF PHENYL HETEROARYL UREAS AS 5HT 2C? RECEPTOR ANTAGONISTS AND UREA COMPOUNDS