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(11)

EP 0 687 299 A1

(12)

(43) Date of publication: 20.12.1995 Bulletin 1995/51 (21) Application number: 94906971.0 (22) Date of filing: 24.02.1994

(51) International Patent Classification (IPC):  C12N 15/ 74( . ) C12N 15/ 77( . ) (86) International application number: PCT/GB1994/000365 (87) International publication number: WO 1994/019460 (01.09.1994 Gazette 1994/20)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 25.02.1993 GB 19930003850 (71) Applicants: Lillehaug, Dag N-1432 Oslo (NO) Birkeland, Nils-Käre N-1432 Oslo (NO)	(72) Inventors: Lillehaug, Dag N-1432 Oslo (NO) Birkeland, Nils-Käre N-1432 Oslo (NO) (74) Representative: Dzieglewska, Hanna Eva  Frank B. Dehn & Co. Imperial House 15-19 Kingsway London WC2B 6UZ London WC2B 6UZ (GB)