(19)
(11) EP 0 691 966 A1

(12)

(43) Date of publication:
17.01.1996 Bulletin 1996/03

(21) Application number: 94911662.0

(22) Date of filing: 23.03.1994
(51) International Patent Classification (IPC): 
C07D 215/ 06( . )
A61K 31/ 50( . )
A61P 11/ 06( . )
A61P 17/ 00( . )
A61P 27/ 16( . )
A61P 37/ 06( . )
A61P 43/ 00( . )
C07D 215/ 12( . )
C07D 215/ 18( . )
C07D 405/ 04( . )
A61K 31/ 47( . )
A61P 11/ 00( . )
A61P 11/ 08( . )
A61P 25/ 20( . )
A61P 29/ 00( . )
A61P 37/ 08( . )
C07D 215/ 04( . )
C07D 215/ 14( . )
C07D 401/ 06( . )
C07D 521/ 00( . )
(86) International application number:
PCT/US1994/003004
(87) International publication number:
WO 1994/022852 (13.10.1994 Gazette 1994/23)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE

(30) Priority: 31.03.1993 US 19930040731

(71) Applicant: SYNTEX (U.S.A.) INC.
Palo Alto California 94304 (US)

(72) Inventors:
  • WILHELM, Robert, Stephen
    Mountain View, CA 94040 (US)
  • FATHEREE, Paul, Ross
    San Francisco, CA 94117 (US)
  • CHIN, Ronnie, Lipp
    Mountain View, CA 94043 (US)

(74) Representative: Witte, Hubert, et al 
F.Hoffmann-La Roche AG Grenzacherstrasse 124 Postfach 32 55
CH-4002 Basel
CH-4002 Basel (CH)

   


(54) QUINOLINES AS TYPE IV PHOSPHODIESTERASE INHIBITORS