(19)

(11)

EP 0 692 979 A1

(12)

(43) Date of publication: 24.01.1996 Bulletin 1996/04 (21) Application number: 94912439.0 (22) Date of filing: 29.03.1994

(51) International Patent Classification (IPC):  A61K 51/ 00( . ) C07F 13/ 00( . ) C07K 5/ 06( . ) C07K 14/ 47( . ) A61K 38/ 00( . ) A61K 51/ 08( . ) C07J 1/ 00( . ) C07K 5/ 08( . ) C07K 14/ 575( . ) (86) International application number: PCT/DE1994/000369 (87) International publication number: WO 1994/022491 (13.10.1994 Gazette 1994/23)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 31.03.1993 DE 19934311021 (71) Applicant: INSTITUT FÜR DIAGNOSTIKFORSCHUNG GmbH AN DER FREIEN UNIVERSITÄT BERLIN D-14050 Berlin (DE)	(72) Inventors: ERBER, Sebastian D-84030 Ergolding (DE) DINKELBORG, Ludger D-13585 Berlin (DE) ROHLFS, Gerhard D-13505 Berlin (DE) SCHULZE, Paul-Eberhard D-14109 Berlin (DE) NOLL, Bernhard D-01705 Freital (DE) (74) Representative: Wablat, Wolfgang, Dr.Dr.  Patentanwalt, Dr. Dr. W. Wablat, Potsdamer Chaussee 48 D-14129 Berlin D-14129 Berlin (DE)