(19)
(11) EP 0 695 170 A1

(12)

(43) Date of publication:
07.02.1996 Bulletin 1996/06

(21) Application number: 94914216.0

(22) Date of filing: 19.04.1994
(51) International Patent Classification (IPC): 
C12N 15/ 09( . )
A61K 47/ 34( . )
C07H 21/ 00( . )
A61K 9/ 16( . )
A61K 48/ 00( . )
(86) International application number:
PCT/US1994/004287
(87) International publication number:
WO 1994/023699 (27.10.1994 Gazette 1994/24)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 19.04.1993 US 19930047672

(71) Applicant: MEDISORB TECHNOLOGIES INTERNATIONAL L.P.
Cincinnati, OH 45242 (US)

(72) Inventors:
  • AMOS, Michael David
    Lebanon, OH 45306 (US)
  • MCELLIGOTT, Sandra Gertrude
    Media, PA 19603 (US)

(74) Representative: Schlich, George William, et al 
Mathys & Squire 100 Grays Inn Road
London WC1X 8AL
London WC1X 8AL (GB)

   


(54) LONG-ACTING TREATMENT BY SLOW-RELEASE DELIVERY OF ANTISENSE OLIGODEOXYRIBONUCLEOTIDES FROM BIODEGRADABLE MICROPARTICLES