(19)
(11) EP 0 700 446 A1

(12)

(43) Date of publication:
13.03.1996 Bulletin 1996/11

(21) Application number: 94919126.0

(22) Date of filing: 18.05.1994
(51) International Patent Classification (IPC): 
G01N 33/ 53( . )
C07K 14/ 47( . )
C07K 16/ 18( . )
C12N 5/ 10( . )
C12N 15/ 02( . )
C12P 21/ 08( . )
C12R 1/ 91( . )
A61K 39/ 395( . )
C07K 14/ 705( . )
C07K 16/ 28( . )
C12N 5/ 20( . )
C12N 15/ 09( . )
G01N 33/ 577( . )
(86) International application number:
PCT/US1994/005277
(87) International publication number:
WO 1994/028161 (08.12.1994 Gazette 1994/27)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT

(30) Priority: 26.05.1993 US 19930068950

(71) Applicant: THE JOHNS HOPKINS UNIVERSITY
Baltimore, MD 21205 (US)

(72) Inventors:
  • BRUSKIN, Arthur
    Huntington Station, NY 11746 (US)
  • JAROSZ, David E.
    Lawrence, MA 01843 (US)
  • JOHNSON, Karen
    Watertown, MA 02172 (US)
  • KINZLER, Kenneth W.
    Baltimore, MD 21234 (US)
  • VOGELSTEIN, Bert
    Baltimore, MD 21208 (US)
  • ZABRECKY, James R.
    Waltham, MA 02154 (US)

(74) Representative: Dean, John Paul, et al 
Withers & Rogers 4 Dyer's Buildings Holborn
London EC1N 2JT
London EC1N 2JT (GB)

   


(54) ANTIBODIES SPECIFIC FOR DCC GENE PRODUCT