(19)

(11)

EP 0 703 787 A1

(12)

(43) Date of publication: 03.04.1996 Bulletin 1996/14 (21) Application number: 94916343.0 (22) Date of filing: 01.06.1994

(51) International Patent Classification (IPC):  A61K 31/ 70( . ) A61P 7/ 00( . ) A61P 43/ 00( . ) A61K 38/ 00( . ) A61K 38/ 46( . ) A61P 35/ 02( . ) C12N 9/ 78( . ) (86) International application number: PCT/GB1994/001190 (87) International publication number: WO 1994/027632 (08.12.1994 Gazette 1994/27)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE Designated Extension States: SI (30) Priority: 01.06.1993 GB 19930011252 (71) Applicant: NYCOMED PHARMA AS N-0301 Oslo (NO)	(72) Inventor: BOYUM, Arne N-2020 Skedsmo (NO) (74) Representative: Matthews, Derek Peter, et al  Frank B. Dehn & Co. Imperial House 15-19 Kingsway London WC2B 6UZ London WC2B 6UZ (GB)