(19)

(11)

EP 0 708 615 A1

(12)

(43) Date of publication: 01.05.1996 Bulletin 1996/18 (21) Application number: 94920190.0 (22) Date of filing: 14.06.1994

(51) International Patent Classification (IPC):  G01N 33/ 66( . ) A61B 5/ 00( . ) (86) International application number: PCT/US1994/006684 (87) International publication number: WO 1995/002357 (26.01.1995 Gazette 1995/05)

(84) Designated Contracting States: DE ES FR GB IT (30) Priority: 16.07.1993 US 19930092975 (71) Applicant: CYGNUS THERAPEUTIC SYSTEMS Redwood City, CA 94063 (US)	(72) Inventor: AZIMI, Nooshin T. Redwood City, CA 94065 (US) (74) Representative: Goldin, Douglas Michael  J.A. KEMP & CO. 14, South Square Gray's Inn London WC1R 5LX London WC1R 5LX (GB)