(19)
(11) EP 0 708 655 A1

(12)

(43) Date of publication:
01.05.1996 Bulletin 1996/18

(21) Application number: 94914048.0

(22) Date of filing: 06.04.1994
(51) International Patent Classification (IPC): 
C12N 15/ 09( . )
A61P 3/ 08( . )
A61P 35/ 00( . )
C07K 14/ 47( . )
C12N 15/ 12( . )
A61K 38/ 00( . )
A61K 38/ 27( . )
A61P 3/ 10( . )
C07K 14/ 46( . )
C12N 1/ 21( . )
C12P 21/ 02( . )
C12R 1/ 19( . )
(86) International application number:
PCT/US1994/003755
(87) International publication number:
WO 1994/022466 (13.10.1994 Gazette 1994/23)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 07.04.1993 US 19930045265

(71) Applicant: AMGEN BOULDER INC.
Boulder, Colorado 80301 (US)

(72) Inventors:
  • COX, George, N.
    Louisville, CO 80027 (US)
  • RUSSELL, Deborah, A.
    Boulder, CO 80303 (US)

(74) Representative: Vossius, Volker, Dr. 
Dr. Volker Vossius, Patentanwaltskanzlei - Rechtsanwaltskanzlei, Holbeinstrasse 5
D-81679 München
D-81679 München (DE)

   


(54) METHODS OF USING INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS