| (84) |
Benannte Vertragsstaaten: |
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AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE |
| (30) |
Priorität: |
04.11.1994 DE 4438918
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| (43) |
Veröffentlichungstag der Anmeldung: |
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08.05.1996 Patentblatt 1996/19 |
| (73) |
Patentinhaber: Roche Diagnostics GmbH |
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68305 Mannheim (DE) |
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| (72) |
Erfinder: |
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- Seela, Frank Prof. Dr.
D-49076 Osnabrück (DE)
- Thomas, Horst, Dr.
D-27801 Dötlingen/Neerstedt (DE)
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| (74) |
Vertreter: Hildebrandt, Martin K. E. |
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Roche Diagnostics GmbH
Patent Department (TR-E)
P.O.Box 11 52
82372 Penzberg
82372 Penzberg (DE) |
| (56) |
Entgegenhaltungen: :
EP-A- 0 251 786
EP-A- 0 286 028
WO-A-93/09127
WO-A-94/22892
WO-A-95/04747
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EP-A- 0 252 683
WO-A-92/06219
WO-A-93/12130
WO-A-94/24144
DE-A- 3 529 478
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- BIOORG. MED. CHEM. LETT., Bd. 4, Nr. 8, 1994, Seiten 971-6, XP002021199 F. SEELA:
"3-Deaza and 7-Deazapurines: Duplex Stability of Oligonucleotides Containing Modified
Adenine and Guanine Bases"
- NUCLEIC ACIDS SYMP. SER., 9.November 1994, Seiten 151-2, XP002021200 F. SEELA: "Oligonucleotides
with Unnatural Bases or an Altered Sugar-Phosphate Backbone"
- NUCLEIC ACIDS RES., Bd. 20, 1992, Seiten 4831-7, XP002021270 K.J. LIVAK EZ AL.: "Detection
of Single Base Differences Using Biotinylated Nucleotides With Very Long Linker Arms"
- CHEMICAL ABSTRACTS, vol. 98, no. 21, 1983 Columbus, Ohio, US; abstract no. 175428,
B.G. HUGHES ET AL.: "2',5'-Oligoadenylates and Related 2',5'-Oligonucleotide Analogs"
Seite 322; XP002021271 & BIOCHEMISTRY, Bd. 22, 1983, Seiten 2116-26,
- CHEMICAL ABSTRACTS, vol. 123, no. 23, 1995 Columbus, Ohio, US; abstract no. 314367,
F. SEELA ET AL.: "Duplex Stabilization of DNA" Seite 946; XP002021272 & HELV. CHIM.
ACTA, Bd. 78, Nr. 1, 1995, Seiten 94-108,
- J. MED. CHEM., Bd. 28, 1985, Seiten 1461-7, XP000655163 H.B. COTTAM ET AL.: "Synthesis
and Biological Activity of Certain 6-Substituted and 2,6-Disubstituted 2'-Deoxytubercidins"
- NUCLEOSIDES, NUCLEOTIDES, Bd. 8, 1989, Seiten 587-97, XP000655157 F. SEELA ET AL.:
"Assignement of Anomeric Configuration of D-Ribo-, Arabino-, 2'-Deoxyribo-, and 2',3'-Dideoxyribonucleosides
by NOE Difference Spectroscopy"
- HELV. CHIM. ACTA, Bd. 77, Nr. 4, 1994, Seiten 897-903, XP000655155 F. SEELA UND H.
THOMAS: "84. Synthesis of Certain 5-Substituted 2'-Deoxytubercidin Derivatives"
- J. HETEROCYCLIC CHEM., Bd. 27, 1990, Seiten 2069-75, XP000655185 K. EGER AT AL.: "Synthesis
of Pyrrolo(2,3-d)pyrimidine Ribosides and thei Potential in Chemotherapeutics"
- HELV. CHIM. ACTA, Bd. 78, 1995, Seiten 1083-90, XP000655172 F. SEELA ET AL.: "88.
7-Substituted 7-Deaza-2'-deoxyguanosines"
- SCIENCE, Bd. 238, 1987, Seiten 336-341, XP000604017 J.M. PROBER ET AL.: "A System
for Rapid DNA Sequencing with Fluorescent Chain-Terminating Dideoxynucleotides"
- PATENT ABSTRACTS OF JAPAN vol. 013, no. 047 & JP 63 241356 A (SEKISUI CHEM CO LTD),
6.Oktober 1988,
- LIEB. ANN. CHEM., 1984, Seiten 708-21, XP000652359 F. SEELA UND H. WINKLER: "Synthese
und Furanosid/ Pyranosid-Isomerisierung von 7-Desaza-2'-desoxy-7-methylguanosin"
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