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<ep-patent-document id="EP95117058B8W1" file="EP95117058W1B8.xml" lang="de" country="EP" doc-number="0710667" kind="B8" correction-code="W1" date-publ="20120314" status="c" dtd-version="ep-patent-document-v1-4">
<SDOBI lang="de"><B000><eptags><B001EP>ATBECHDEDKESFRGBGRITLILUNLSE..PTIE..................................................................</B001EP><B005EP>J</B005EP><B007EP>DIM360 Ver 2.15 (14 Jul 2008) -  2999001/0</B007EP><B070EP>Die Akte enthält technische Angaben, die nach dem Eingang der Anmeldung eingereicht wurden und die nicht in dieser Patentschrift enthalten sind.</B070EP></eptags></B000><B100><B110>0710667</B110><B120><B121>KORRIGIERTE EUROPÄISCHE PATENTSCHRIFT</B121></B120><B130>B8</B130><B132EP>B1</B132EP><B140><date>20120314</date></B140><B150><B151>W1</B151><B153>73</B153><B155><B1551>de</B1551><B1552>Bibliographie</B1552><B1551>en</B1551><B1552>Bibliography</B1552><B1551>fr</B1551><B1552>Bibliographie</B1552></B155></B150><B190>EP</B190></B100><B200><B210>95117058.8</B210><B220><date>19951030</date></B220><B240><B241><date>19980310</date></B241><B242><date>20010109</date></B242></B240><B250>de</B250><B251EP>de</B251EP><B260>de</B260></B200><B300><B310>4438918</B310><B320><date>19941104</date></B320><B330><ctry>DE</ctry></B330></B300><B400><B405><date>20120314</date><bnum>201211</bnum></B405><B430><date>19960508</date><bnum>199619</bnum></B430><B450><date>20111214</date><bnum>201150</bnum></B450><B452EP><date>20110721</date></B452EP><B480><date>20120314</date><bnum>201211</bnum></B480></B400><B500><B510EP><classification-ipcr sequence="1"><text>C07H  21/00        20060101AFI19960304BHEP        </text></classification-ipcr><classification-ipcr sequence="2"><text>C07H  19/14        20060101ALI19960304BHEP        </text></classification-ipcr><classification-ipcr sequence="3"><text>A61K  31/70        20060101ALI19960304BHEP        </text></classification-ipcr></B510EP><B540><B541>de</B541><B542>Modifizierte Oligonukleotide, deren Herstellung sowie deren Verwendung</B542><B541>en</B541><B542>Modified oligonucleotides, their preparation and their use</B542><B541>fr</B541><B542>Oligonucléotides modifiés, leur préparation et leur utilisation</B542></B540><B560><B561><text>EP-A- 0 251 786</text></B561><B561><text>EP-A- 0 252 683</text></B561><B561><text>EP-A- 0 286 028</text></B561><B561><text>WO-A-92/06219</text></B561><B561><text>WO-A-93/09127</text></B561><B561><text>WO-A-93/12130</text></B561><B561><text>WO-A-94/22892</text></B561><B561><text>WO-A-94/24144</text></B561><B561><text>WO-A-95/04747</text></B561><B561><text>DE-A- 3 529 478</text></B561><B562><text>BIOORG. MED. CHEM. LETT., Bd. 4, Nr. 8, 1994, Seiten 971-6, XP002021199 F. SEELA: "3-Deaza and 7-Deazapurines: Duplex Stability of Oligonucleotides Containing Modified Adenine and Guanine Bases"</text></B562><B562><text>NUCLEIC ACIDS SYMP. SER., 9.November 1994, Seiten 151-2, XP002021200 F. SEELA: "Oligonucleotides with Unnatural Bases or an Altered Sugar-Phosphate Backbone"</text></B562><B562><text>NUCLEIC ACIDS RES., Bd. 20, 1992, Seiten 4831-7, XP002021270 K.J. LIVAK EZ AL.: "Detection of Single Base Differences Using Biotinylated Nucleotides With Very Long Linker Arms"</text></B562><B562><text>CHEMICAL ABSTRACTS, vol. 98, no. 21, 1983 Columbus, Ohio, US; abstract no. 175428, B.G. HUGHES ET AL.: "2',5'-Oligoadenylates and Related 2',5'-Oligonucleotide Analogs" Seite 322; XP002021271 &amp; BIOCHEMISTRY, Bd. 22, 1983, Seiten 2116-26,</text></B562><B562><text>CHEMICAL ABSTRACTS, vol. 123, no. 23, 1995 Columbus, Ohio, US; abstract no. 314367, F. SEELA ET AL.: "Duplex Stabilization of DNA" Seite 946; XP002021272 &amp; HELV. CHIM. ACTA, Bd. 78, Nr. 1, 1995, Seiten 94-108,</text></B562><B562><text>J. MED. CHEM., Bd. 28, 1985, Seiten 1461-7, XP000655163 H.B. COTTAM ET AL.: "Synthesis and Biological Activity of Certain 6-Substituted and 2,6-Disubstituted 2'-Deoxytubercidins"</text></B562><B562><text>NUCLEOSIDES, NUCLEOTIDES, Bd. 8, 1989, Seiten 587-97, XP000655157 F. SEELA ET AL.: "Assignement of Anomeric Configuration of D-Ribo-, Arabino-, 2'-Deoxyribo-, and 2',3'-Dideoxyribonucleosides by NOE Difference Spectroscopy"</text></B562><B562><text>HELV. CHIM. ACTA, Bd. 77, Nr. 4, 1994, Seiten 897-903, XP000655155 F. SEELA UND H. THOMAS: "84. Synthesis of Certain 5-Substituted 2'-Deoxytubercidin Derivatives"</text></B562><B562><text>J. HETEROCYCLIC CHEM., Bd. 27, 1990, Seiten 2069-75, XP000655185 K. EGER AT AL.: "Synthesis of Pyrrolo(2,3-d)pyrimidine Ribosides and thei Potential in Chemotherapeutics"</text></B562><B562><text>HELV. CHIM. ACTA, Bd. 78, 1995, Seiten 1083-90, XP000655172 F. SEELA ET AL.: "88. 7-Substituted 7-Deaza-2'-deoxyguanosines"</text></B562><B562><text>SCIENCE, Bd. 238, 1987, Seiten 336-341, XP000604017 J.M. PROBER ET AL.: "A System for Rapid DNA Sequencing with Fluorescent Chain-Terminating Dideoxynucleotides"</text></B562><B562><text>PATENT ABSTRACTS OF JAPAN vol. 013, no. 047 &amp; JP 63 241356 A (SEKISUI CHEM CO LTD), 6.Oktober 1988,</text></B562><B562><text>LIEB. ANN. CHEM., 1984, Seiten 708-21, XP000652359 F. SEELA UND H. WINKLER: "Synthese und Furanosid/ Pyranosid-Isomerisierung von 7-Desaza-2'-desoxy-7-methylguanosin"</text></B562></B560></B500><B700><B720><B721><snm>Seela, Frank Prof. Dr.</snm><adr><str>Gutenbergstrasse 44</str><city>D-49076 Osnabrück</city><ctry>DE</ctry></adr></B721><B721><snm>Thomas, Horst, Dr.</snm><adr><str>Fasanenweg 12</str><city>D-27801 Dötlingen/Neerstedt</city><ctry>DE</ctry></adr></B721></B720><B730><B731><snm>Roche Diagnostics GmbH</snm><iid>100209598</iid><irf>23510 EP-HIL</irf><adr><str>Sandhofer Strasse 116</str><city>68305 Mannheim</city><ctry>DE</ctry></adr></B731></B730><B740><B741><snm>Hildebrandt, Martin K. E.</snm><iid>100052340</iid><adr><str>Roche Diagnostics GmbH 
Patent Department (TR-E) 
P.O.Box 11 52</str><city>82372 Penzberg</city><ctry>DE</ctry></adr></B741></B740></B700><B800><B840><ctry>AT</ctry><ctry>BE</ctry><ctry>CH</ctry><ctry>DE</ctry><ctry>DK</ctry><ctry>ES</ctry><ctry>FR</ctry><ctry>GB</ctry><ctry>GR</ctry><ctry>IE</ctry><ctry>IT</ctry><ctry>LI</ctry><ctry>LU</ctry><ctry>NL</ctry><ctry>PT</ctry><ctry>SE</ctry></B840><B880><date>19970910</date><bnum>199737</bnum></B880></B800></SDOBI>
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