(19)

(11)

EP 0 711 147 A1

(12)

(43) Date of publication: 15.05.1996 Bulletin 1996/20 (21) Application number: 94922703.0 (22) Date of filing: 22.07.1994

(51) International Patent Classification (IPC):  A61K 9/ 107( . ) A61K 47/ 02( . ) A61K 9/ 00( . ) A61K 47/ 32( . ) (86) International application number: PCT/US1994/008331 (87) International publication number: WO 1995/003784 (09.02.1995 Gazette 1995/07)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 28.07.1993 US 19930103028 29.09.1993 US 19930128151 (71) Applicant: INSITE VISION INCORPORATED Alameda, CA 94501 (US)	(72) Inventors: BOWMAN, Lyle M. Pleasanton, CA 94566 (US) PATEL, Rajesh San Mateo, CA 94404 (US) TSAO, Sheng-Wan Min-hu Road Hsing-Chu Taiwan 300 (CN) VO, Hoa Vinh Alameda, CA 94501 (US) (74) Representative: Goldin, Douglas Michael, et al  J.A. KEMP & CO. 14, South Square Gray's Inn London WC1R 5LX London WC1R 5LX (GB)