(19)

(11)

EP 0 711 153 A1

(12)

(43) Date of publication: 15.05.1996 Bulletin 1996/20 (21) Application number: 94920731.0 (22) Date of filing: 14.06.1994

(51) International Patent Classification (IPC):  A61K 9/ 70( . ) (86) International application number: PCT/US1994/006681 (87) International publication number: WO 1995/000122 (05.01.1995 Gazette 1995/02)

(84) Designated Contracting States: DE ES FR GB IT (30) Priority: 24.06.1993 US 19930082926 (71) Applicant: CYGNUS THERAPEUTIC SYSTEMS Redwood City, CA 94063 (US)	(72) Inventors: CONNORS, Dan W. Redwood City, CA 94063 (US) CHEN, Jia Foster City, CA 94404 (US) HUIE, Scott A. Redwood City, CA 94065 (US) (74) Representative: Price, Nigel John King  J.A. KEMP & CO. 14 South Square Gray's Inn London WC1R 5LX London WC1R 5LX (GB)