(19)
(11) EP 0 711 284 A1

(12)

(43) Date of publication:
15.05.1996 Bulletin 1996/20

(21) Application number: 94925381.0

(22) Date of filing: 22.07.1994
(51) International Patent Classification (IPC): 
C07D 277/ 68( . )
A61K 31/ 4184( . )
A61K 31/ 423( . )
A61K 31/ 428( . )
A61P 3/ 00( . )
A61P 3/ 06( . )
A61P 9/ 10( . )
A61P 25/ 26( . )
C07D 235/ 26( . )
C07F 9/ 40( . )
A61K 31/ 415( . )
A61K 31/ 42( . )
A61K 31/ 425( . )
A61P 1/ 04( . )
A61P 3/ 04( . )
A61P 3/ 08( . )
A61P 25/ 24( . )
C07C 217/ 84( . )
C07D 263/ 58( . )
C07F 9/ 6506( . )
(86) International application number:
PCT/EP1994/002434
(87) International publication number:
WO 1995/004047 (09.02.1995 Gazette 1995/07)
(84) Designated Contracting States:
BE CH DE FR GB IT LI NL

(30) Priority: 31.07.1993 GB 19930015930
22.10.1993 GB 19930021875
22.11.1993 GB 19930023982

(71) Applicant: SMITHKLINE BEECHAM PLC
Brentford, Middlesex TW8 9EP (GB)

(72) Inventors:
  • BEELEY, Lee James, SmithKline Beecham Pharm.
    Epsom, Suurey KT18 5XQ (GB)
  • BERGE, John Michael, SmithKline Beecham Pharm.
    Epsom, Surrey KT18 5XQ (GB)

(74) Representative: Rutter, Keith, Dr., et al 
SmithKline Beecham plc Corporate Intellectual Property SB House Great West Road
Brentford, Middlesex TW8 9BD
Brentford, Middlesex TW8 9BD (GB)

   


(54) 2-BENZOHETEROCYCLYLOXY OR THIOPROPANOLAMINE DERIVATIVES WITH ADRENO RECEPTOR AGONIST ACTIVITY