(19)

(11)

EP 0 717 776 A1

(12)

(43) Date of publication: 26.06.1996 Bulletin 1996/26 (21) Application number: 94921606.0 (22) Date of filing: 19.07.1994

(51) International Patent Classification (IPC):  C12N 9/ 88( . ) C12N 9/ 96( . ) (86) International application number: PCT/DK1994/000289 (87) International publication number: WO 1995/004137 (09.02.1995 Gazette 1995/07)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE (30) Priority: 28.07.1993 DK 19930000880 (71) Applicant: NOVO NORDISK A/S DK-2880 Bagsvaerd (DK)	(72) Inventors: HEJNAES, Kim DK-2800 Lyngby (DK) MOODY, Alister J. DK-2920 Charlottenlund (DK) MARSHALL, Michael Owen DK-2920 Charlottenlund (DK)