(19)

(11)

EP 0 726 775 A1

(12)

(43) Date of publication: 21.08.1996 Bulletin 1996/34 (21) Application number: 95902425.0 (22) Date of filing: 02.11.1994

(51) International Patent Classification (IPC):  A61K 39/ 118( . ) (86) International application number: PCT/US1994/012626 (87) International publication number: WO 1995/012411 (11.05.1995 Gazette 1995/20)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 03.11.1993 US 19930147636 (71) Applicant: PFIZER INC. New York, N.Y. 10017-5755 (US)	(72) Inventors: SABARA, Marta Iris Lincoln, NE 68506 (US) SANDBULTE, James Evan Lincoln, NE 68506 (US) TERWEE, Julie Ann Lincoln, NE 68504 (US) (74) Representative: Baillie, Iain Cameron, et al  c/o Ladas & Parry Altheimer Eck 2 80331 München 80331 München (DE)