(19)

(11)

EP 0 726 777 A1

(12)

(43) Date of publication: 21.08.1996 Bulletin 1996/34 (21) Application number: 94932028.0 (22) Date of filing: 25.10.1994

(51) International Patent Classification (IPC):  C12N 15/ 09( . ) A61K 38/ 00( . ) A61K 39/ 385( . ) A61P 29/ 00( . ) A61P 43/ 00( . ) C12N 1/ 21( . ) C12P 21/ 02( . ) A61K 9/ 127( . ) A61K 39/ 00( . ) A61P 25/ 00( . ) A61P 37/ 00( . ) C07K 14/ 74( . ) C12N 15/ 12( . ) C12R 1/ 19( . ) (86) International application number: PCT/US1994/012231 (87) International publication number: WO 1995/011702 (04.05.1995 Gazette 1995/19)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 25.10.1993 US 19930143575 (71) Applicant: ANERGEN, INC. Redwood City, CA 94063 (US)	(72) Inventors: RHODES, Eric T. Vallejo, CA 94591 (US) NAG, Bishwajit Pacifica, CA 94044 (US) (74) Representative: Walton, Seán Malcolm, et al  Mewburn Ellis, York House, 23 Kingsway London WC2B 6HP London WC2B 6HP (GB)