(19)

(11)

EP 0 728 010 A1

(12)

(43) Date of publication: 28.08.1996 Bulletin 1996/35 (21) Application number: 93925097.0 (22) Date of filing: 28.10.1993

(51) International Patent Classification (IPC):  A61K( . ) A61K 38/ 00( . ) A61K 38/ 22( . ) A61K 35/ 55( . ) A61K 38/ 08( . ) (86) International application number: PCT/US1993/010343 (87) International publication number: WO 1995/011688 (04.05.1995 Gazette 1995/19)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE (71) Applicant: Sciclone Pharmaceuticals San Mateo, CA 94404 (US)	(72) Inventors: SCHARSCHMIDT, Bruce F. San Francisco, CA 94127 (US) BAXTER, John D. San Francisco, CA 94127 (US) HORWITZ, David L. Hillsborough, CA 94010 (US) (74) Representative: Goldin, Douglas Michael, et al  J.A. KEMP & CO. 14, South Square Gray's Inn London WC1R 5LX London WC1R 5LX (GB)