5,6-DIHYDROPYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS - Patent 0729464

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(11)

EP 0 729 464 A1

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(43)	Date of publication:
	04.09.1996 Bulletin 1996/36

(21)	Application number: 95900429.0

(22)	Date of filing: 26.10.1994

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International Patent Classification (IPC):

C07D 335/ 02^{( . )}
A61K 31/ 351^{( . )}
A61K 31/ 365^{( . )}
A61K 31/ 44^{( . )}
A61K 31/ 4433^{( . )}
A61P 31/ 04^{( . )}
A61P 31/ 18^{( . )}
C07C 381/ 04^{( . )}
C07D 211/ 86^{( . )}
C07D 309/ 38^{( . )}
C07D 405/ 04^{( . )}
C07D 407/ 06^{( . )}

A61K 31/ 35^{( . )}
A61K 31/ 352^{( . )}
A61K 31/ 366^{( . )}
A61K 31/ 443^{( . )}
A61K 31/ 48^{( . )}
A61P 31/ 12^{( . )}
C07C 323/ 22^{( . )}
C07D 211/ 84^{( . )}
C07D 309/ 32^{( . )}
C07D 311/ 96^{( . )}
C07D 405/ 12^{( . )}
C07D 409/ 04^{( . )}

(86)	International application number:
	PCT/US1994/012269

(87)	International publication number:
	WO 1995/014012 (26.05.1995 Gazette 1995/22)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
	Designated Extension States:
	LT SI

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Priority:

19.11.1993 US 19930155443
12.10.1994 US 19940319820

(60)	Divisional application:
	01114943.2 / 1142887

(71)	Applicant: PARKE, DAVIS & COMPANY
	Morris Plains New Jersey 07950 (US)

(72)	Inventors:
	ELLSWORTH, Edmund, Lee Brighton, Michigan 48116 (US) LUNNEY, Elizabeth Ann Arbor, MI 48103 (US) TAIT, Bradley, Dean Canton, MI 48187 (US)

(74)	Representative: Mansmann, Ivo, et al
	Warner-Lambert Company, Legal Division, Legal Department, c/o Gödecke AG 79090 Freiburg 79090 Freiburg (DE)

(54)	5,6-DIHYDROPYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS