(19)

(11)

EP 0 734 256 A1

(12)

(43) Date of publication: 02.10.1996 Bulletin 1996/40 (21) Application number: 95904909.0 (22) Date of filing: 16.12.1994

(51) International Patent Classification (IPC):  A61K 31/ 12( . ) A61P 29/ 00( . ) A61P 25/ 04( . ) (86) International application number: PCT/US1994/014405 (87) International publication number: WO 1995/016443 (22.06.1995 Gazette 1995/26)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE (30) Priority: 17.12.1993 US 19930169347 (71) Applicant: THE PROCTER & GAMBLE COMPANY Cincinnati, Ohio 45202 (US)	(72) Inventors: HUDEC, Thomas Tod Wyandotte, MI 48192 (US) LOOMANS, Maurice Edward Cincinnati, OH 45239 (US) SHULMAN, Joel Ira Cincinnati, OH 45215 (US) (74) Representative: Brooks, Maxim Courtney  Rusham Park, Whitehall Lane Egham, Surrey TW20 9NW Egham, Surrey TW20 9NW (GB)