PHENYL HETEROCYCLES AS COX-2 INHIBITORS - Patent 0739340

(19)

(11)

EP 0 739 340 A1

(12)

(43)	Date of publication:
	30.10.1996 Bulletin 1996/44

(21)	Application number: 95903727.0

(22)	Date of filing: 19.12.1994

(51)

International Patent Classification (IPC):

A61K 31/ 10^{( . )}
A61K 31/ 18^{( . )}
A61K 31/ 47^{( . )}
A61P 43/ 00^{( . )}
C07C 311/ 29^{( . )}
C07C 311/ 49^{( . )}
C07D 275/ 02^{( . )}
C07D 307/ 38^{( . )}
C07D 333/ 18^{( . )}
C07D 405/ 04^{( . )}

A61K 31/ 16^{( . )}
A61K 31/ 365^{( . )}
A61P 29/ 00^{( . )}
C07C 311/ 15^{( . )}
C07C 311/ 46^{( . )}
C07C 317/ 24^{( . )}
C07D 277/ 26^{( . )}
C07D 307/ 58^{( . )}
C07D 333/ 38^{( . )}

(86)	International application number:
	PCT/CA1994/000688

(87)	International publication number:
	WO 1995/018799 (13.07.1995 Gazette 1995/30)

(84)	Designated Contracting States:
	AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE
	Designated Extension States:
	LT SI

(30)

Priority:

10.01.1994 US 19940179467

(71)	Applicant: MERCK FROSST CANADA INC.
	Kirkland Quebec H9H 3L1 (CA)

(72)	Inventors:
	DUCHARME, Yves Montreal, Quebec H4B 2W6 (CA) GAUTHIER, Jacques, Yves Apartment 2 Laval, Quebec H7N 5Z4 (CA) PRASIT, Petpiboon Kirkland, Quebec H9H 5A6 (CA) LEBLANC, Yves Kirkland, Quebec H9J 3Y3 (CA) WANG, Zhaoyin Pierrefonds, Quebec H8Z 1Y5 (CA) LEGER, Serge Dollard Des Ormeaux, Quebec H9B 3E5 (CA) THERIEN, Michel Laval, Quebec H7R 2R2 (CA)

(74)	Representative: Cole, William Gwyn, et al
	European Patent Department Merck & Co., Inc. Terlings Park Eastwick Road Harlow Essex CM20 2QR Harlow Essex CM20 2QR (GB)

(54)	PHENYL HETEROCYCLES AS COX-2 INHIBITORS