(19)

(11)

EP 0 740 549 A1

(12)

(43) Date of publication: 06.11.1996 Bulletin 1996/45 (21) Application number: 95908606.0 (22) Date of filing: 23.01.1995

(51) International Patent Classification (IPC):  A61K 45/ 00( . ) A61K 31/ 40( . ) A61P 27/ 02( . ) A61K 31/ 00( . ) A61K 31/ 401( . ) (86) International application number: PCT/US1995/000809 (87) International publication number: WO 1995/019764 (27.07.1995 Gazette 1995/32)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 21.01.1994 US 19940184118 (71) Applicants: JAVITT, Jonathan C. Washington, DC 20007 (US) McDONNELL, Peter Los Angeles, CA 90033 (US) JAVITT, Norman B. New York, NY 10016 (US)	(72) Inventors: JAVITT, Jonathan C. Washington, DC 20007 (US) McDONNELL, Peter Los Angeles, CA 90033 (US) JAVITT, Norman B. New York, NY 10016 (US) (74) Representative: Bizley, Richard Edward, et al  Hepworth, Lawrence, Bryer & Bizley Merlin House Falconry Court Baker's Lane Epping Essex CM16 5DQ Epping Essex CM16 5DQ (GB)