(19)
(11) EP 0 748 313 A1

(12)

(43) Date of publication:
18.12.1996 Bulletin 1996/51

(21) Application number: 95912688.0

(22) Date of filing: 03.03.1995
(51) International Patent Classification (IPC): 
A61K 31/ 415( . )
A61P 1/ 04( . )
A61P 19/ 10( . )
A61P 35/ 02( . )
C07D 233/ 54( . )
C07D 233/ 68( . )
A61P 1/ 02( . )
A61P 17/ 00( . )
A61P 29/ 00( . )
A61P 43/ 00( . )
C07D 233/ 64( . )
(86) International application number:
PCT/US1995/002606
(87) International publication number:
WO 1995/023790 (08.09.1995 Gazette 1995/38)
(84) Designated Contracting States:
BE CH DE FR GB IT LI NL

(30) Priority: 03.03.1994 GB 19940004046

(71) Applicant: SMITHKLINE BEECHAM CORPORATION
King of Prussia, PA 19406-0939 (US)

(72) Inventors:
  • FRAZEE, James, Simpson
    Sewell, NJ 08080 (US)
  • GLEASON, John, Gerald
    Downingtown, PA 19335 (US)
  • METCALF, Brian, Walter
    Radnor, PA 19087 (US)

(74) Representative: Summersell, Richard John, Dr. 
SmithKline Beecham plc, Corporate Intellectual Property, Two New Horizons Court
Brentford, Middlesex TW8 9EP
Brentford, Middlesex TW8 9EP (GB)

   


(54) CYTOKINE INHIBITING IMIDAZOLE SUBSTITUTED HYDROXAMIC ACID DERIVATIVES