(19)

(11)

EP 0 749 292 A1

(12)

(43) Date of publication: 27.12.1996 Bulletin 1996/52 (21) Application number: 95915247.0 (22) Date of filing: 12.04.1995

(51) International Patent Classification (IPC):  A61F 2/ 08( . ) A61L 27/ 52( . ) A61L 27/ 34( . ) (86) International application number: PCT/GB1995/000836 (87) International publication number: WO 1995/027449 (19.10.1995 Gazette 1995/45)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 12.04.1994 GB 19940007237 (71) Applicant: THE SECRETARY OF STATE FOR HEALTH London SW1A 2NS (GB)	(72) Inventors: PICKLES, David, Martin Bristol BS2 8EJ (GB) GOODSHIP, Allen, Edward Bristol BS2 8EJ (GB) HIGHGATE, Donald, James Guildford,Surrey GU5 9NZ (GB) SCOTT, Robert, Andrew New Milton,Hampshire BH25 525 5NN (GB) (74) Representative: Skelton, Stephen Richard, et al  D/IPR1, 7C/2/A31, MOD(PE) Abbey Wood, P.O. Box 702 Bristol BS12 7DU Bristol BS12 7DU (GB)