(19)

(11)

EP 0 749 474 A1

(12)

(43) Date of publication: 27.12.1996 Bulletin 1996/52 (21) Application number: 95912741.0 (22) Date of filing: 07.03.1995

(51) International Patent Classification (IPC):  A61F 2/ 02( . ) A61K 9/ 50( . ) B01D 39/ 16( . ) B01D 67/ 00( . ) B01D 69/ 12( . ) B01J 13/ 02( . ) B81C 1/ 00( . ) C23C 16/ 01( . ) A61K 9/ 00( . ) A61K 9/ 52( . ) B01D 39/ 20( . ) B01D 69/ 02( . ) B01D 71/ 02( . ) B81B 1/ 00( . ) C04B 41/ 45( . ) G03F 7/ 00( . ) (86) International application number: PCT/US1995/002752 (87) International publication number: WO 1995/024472 (14.09.1995 Gazette 1995/39)

(84) Designated Contracting States: FR GB (30) Priority: 07.03.1994 US 19940207457 07.03.1994 US 19940207459 06.06.1994 US 19940254330 (71) Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA Oakland, California 94612-3550 (US)	(72) Inventors: KELLER, Christopher G., Apartment 7B Albany, CA 94706 (US) FERRARI, Mauro Walnut Creek, CA 94596 (US) (74) Representative: Wilkinson, Stephen John  Stevens, Hewlett & Perkins 1 St. Augustine's Place Bristol BS1 4UD Bristol BS1 4UD (GB)