(19)

(11)

EP 0 750 500 A1

(12)

(43) Date of publication: 02.01.1997 Bulletin 1997/01 (21) Application number: 95910559.0 (22) Date of filing: 07.03.1995

(51) International Patent Classification (IPC):  C07D 257/ 04( . ) A61P 13/ 02( . ) A61K 31/ 41( . ) A61P 15/ 00( . ) (86) International application number: PCT/EP1995/000831 (87) International publication number: WO 1995/024901 (21.09.1995 Gazette 1995/40)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 17.03.1994 CH 19940000800 (71) Applicant: CIBA-GEIGY AG 4002 Basel (CH)	(72) Inventors: DE GASPARO, Marc CH-2842 Rossemaison (CH) LEVENS, Nigel CH-4123 Allschwil (CH)