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EP 0 751 943 A1

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(43) Date of publication: 08.01.1997 Bulletin 1997/02 (21) Application number: 95912490.0 (22) Date of filing: 13.03.1995

(51) International Patent Classification (IPC):  C07D 417/ 12( . ) A61K 31/ 415( . ) A61K 31/ 44( . ) A61K 31/ 50( . ) A61K 31/ 535( . ) A61P 31/ 04( . ) C07D 417/ 14( . ) C07D 521/ 00( . ) A61K 31/ 41( . ) A61K 31/ 425( . ) A61K 31/ 495( . ) A61K 31/ 505( . ) A61K 31/ 54( . ) A61P 31/ 10( . ) C07D 513/ 04( . ) (86) International application number: PCT/KR1995/000019 (87) International publication number: WO 1995/025107 (21.09.1995 Gazette 1995/40)

(84) Designated Contracting States: CH DE FR GB IT LI (30) Priority: 12.03.1994 KR 19940004917 12.03.1994 KR 19940004918 01.06.1994 KR 19940012285 (71) Applicant: Yuhan Corporation Seoul 156-020 (KR)

(72) Inventors: LEE, Jong, Wook Kyonggi-do 427-040 (KR) CHAE, Jeong, Seok Kwanak-gu, Seoul 151-029 (KR) KANG, Heui, Il Kunpo-si, Kyonggi-do 435-042 (KR) LEE, Chun, Ho Kwanak-gu, Seoul 151-053 (KR) PARK, Soo, Bong Kwacheon-si, Kyonggi-do 427-010 (KR) YI, Won, Hui Euiwang-si, Kyonggi-do 437-070 (KR) KIM, Chul, 103-1509, Woncheon Jukong Apart. Suwon-si, Kyonggi-do 441-390 (KR) (74) Representative: von Samson-Himmelstjerna, Friedrich R., Dipl.-Phys., et al  SAMSON & PARTNER Widenmayerstrasse 5 80538 München 80538 München (DE)