(19)

(11)

EP 0 751 949 A1

(12)

(43) Date of publication: 08.01.1997 Bulletin 1997/02 (21) Application number: 95903626.0 (22) Date of filing: 01.12.1994

(51) International Patent Classification (IPC):  C07H 21/ 04( . ) A61K 48/ 00( . ) A61P 31/ 12( . ) C07H 21/ 02( . ) A61K 38/ 00( . ) A61K 31/ 70( . ) A61P 1/ 16( . ) C07H 21/ 00( . ) C12N 15/ 113( . ) (86) International application number: PCT/US1994/013687 (87) International publication number: WO 1995/017414 (29.06.1995 Gazette 1995/27)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 23.12.1993 US 19930172538 (71) Applicant: APOLLON, INC. Malvern, PA 19355-1423 (US)	(72) Inventors: CONEY, Leslie, R. Rosemont, PA 19010 (US) PACHUK, Catherine, J. Lansdowne, PA 19050 (US) YOON, Kyonggeun Berwyn, PA 19312 (US) (74) Representative: Dzieglewska, Hanna Eva, et al  Frank B. Dehn & Co., European Patent Attorneys, 179 Queen Victoria Street London EC4V 4EL London EC4V 4EL (GB)