(19)
(11) EP 0 752 008 A1

(12)

(43) Date of publication:
08.01.1997 Bulletin 1997/02

(21) Application number: 95911826.0

(22) Date of filing: 17.02.1995
(51) International Patent Classification (IPC): 
C12N 15/ 09( . )
A61K 39/ 395( . )
C07K 14/ 545( . )
C12N 9/ 38( . )
C12N 15/ 00( . )
C12P 21/ 08( . )
C40B 40/ 02( . )
G01N 33/ 566( . )
A61K 38/ 00( . )
C07K 14/ 435( . )
C07K 16/ 00( . )
C12N 9/ 86( . )
C12N 15/ 10( . )
C12Q 1/ 68( . )
G01N 33/ 53( . )
(86) International application number:
PCT/US1995/002126
(87) International publication number:
WO 1995/022625 (24.08.1995 Gazette 1995/36)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 17.02.1994 US 19940198431

(60) Divisional application:
01100962.8 / 1094108

(60) Divisional application:
01123328.5 / 1205547

(60) Divisional application:
98122040.3 / 0934999

(71) Applicant: AFFYMAX TECHNOLOGIES N.V.
Willemstad, CuraƧao (AN)

(72) Inventors:
  • STEMMER, Willem P.C.
    Los Gatos, CA 95030 (US)
  • CRAMERI, Andreas
    Mountain View, CA 94040 (US)

(74) Representative: Bizley, Richard Edward, et al 
Hepworth, Lawrence, Bryer & Bizley Merlin House Falconry Court Baker's Lane
Epping Essex CM16 5DQ
Epping Essex CM16 5DQ (GB)

   


(54) DNA MUTAGENESIS BY RANDOM FRAGMENTATION AND REASSEMBLY