(19)

(11)

EP 0 752 867 A1

(12)

(43) Date of publication: 15.01.1997 Bulletin 1997/03 (21) Application number: 94908664.0 (22) Date of filing: 26.01.1994

(51) International Patent Classification (IPC):  A01N 1/ 02( . ) A61K 35/ 12( . ) A61K 35/ 26( . ) A61K 38/ 00( . ) A61K 38/ 22( . ) A61K 38/ 44( . ) A61P 7/ 00( . ) A61P 31/ 12( . ) C12N 5/ 078( . ) A61K 31/ 23( . ) A61K 35/ 14( . ) A61K 36/ 48( . ) A61K 38/ 21( . ) A61K 38/ 36( . ) A61K 48/ 00( . ) A61P 31/ 04( . ) A61P 37/ 00( . ) C12N 5/ 0789( . ) (86) International application number: PCT/US1994/001033 (87) International publication number: WO 1994/016715 (04.08.1994 Gazette 1994/18)

(84) Designated Contracting States: AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE (30) Priority: 27.01.1993 US 19930009593 25.01.1994 US 19940188376 (71) Applicant: HEMOSOL INC. Etobicoke, Ontario M9W 4Z4 (CA)	(72) Inventors: RUNSTADLER, Peter, W. Hanover, NH 03755 (US) PANG, Roy, H., L. Etna, NH 03750 (US) (74) Representative: Eyles, Christopher Thomas  W.P. THOMPSON & CO. Celcon House 289-293 High Holborn London WC1V 7HU London WC1V 7HU (GB)