(19)
(11) EP 0 752 880 A1

(12)

(43) Date of publication:
15.01.1997 Bulletin 1997/03

(21) Application number: 95916183.0

(22) Date of filing: 07.04.1995
(51) International Patent Classification (IPC): 
A61K 38/ 00( . )
A61K 38/ 21( . )
A61K 38/ 28( . )
A61P 3/ 08( . )
A61P 27/ 02( . )
A61P 31/ 04( . )
A61P 43/ 00( . )
 A61K 38/ 17( . )
A61K 38/ 26( . )
A61K 39/ 00( . )
A61P 25/ 00( . )
A61P 29/ 00( . )
A61P 37/ 00( . )
C07K 14/ 47( . )
(86) International application number:
PCT/US1995/004120
(87) International publication number:
WO 1995/027499 (19.10.1995 Gazette 1995/45)
(84) Designated Contracting States:
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

(30) Priority: 08.04.1994 US 19940225372

(71) Applicant: BRIGHAM AND WOMEN'S HOSPITAL
Boston, Massachusetts 02115 (US)

(72) Inventors:
  • HAFLER, David A.
    West Newton, MA 02165 (US)
  • WEINER, Howard L.
    Brookline, MA 02146 (US)

(74) Representative: Klitzsch, Gottfried 
Patentanwälte Grünecker, Kinkeldey, Stockmair & Partner Maximilianstrasse 58
80538 München
80538 München (DE)

   


(54) TREATMENT OF AUTOIMMUNE DISEASE USING ORAL TOLERIZATION AND/OR TYPE I INTERFERON